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Research has indicated that lactate that has accumulated within cancer cells is transported extracellularly by the monocarboxylate transporter MCT4, which not only facilitates the acceleration of glycolytic flux but also increases the acidity of the TME and promotes angiogenesis [71]

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Cragga GM, Pezzutob JM

"Antioxidant mechanisms of glutathione in skin protection: From molecular pathways to clinical applications." Free Radical Biology and Medicine, 168, 187-202.

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