The benefits of significant weight loss and improved health outcomes far outweigh these manageable side effects
But I want to be clear: that is not the primary thing I am talking about here
& Kang., S
The terms used were inborn errors of metabolism, metabolic defects, child, heart, cardiac, mitochondrial disorders, carnitine, fatty acid metabolism, acidemia, storage disorders, Pompe, Fabry, Barth syndrome, Smith-Lemli-Opitz, congenital disorders of glycosylation, cardiomyopathy, arrhythmia, heart rhythm disorders, valve, congenital heart disorders, and structural heart disorders
The degree of degradation is unknown, and using it would introduce a massive variable that could invalidate your results
However, these studies cannot definitely establish the absence of any metformin-associated risk because of methodological limitations, including small sample size and inconsistent comparator groups