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Bdnf flox/flox;Lepr-ires-Cre mice and Bdnf flox/flox littermate controls were injected with leptin (5 mg/kg, i.p.) 2 h before the forced swim test

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Factors such as potency, additional ingredients, and formulation affect their efficacy

These regimens are calibrated to maximize tumor cytotoxicity while allowing sufficient recovery time for healthy tissue

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