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The pl of a peptide may be theoretically calculated from the pK values of its amino acids and of the terminal amine and carboxyl groups and can be used to predict the solubility of the peptide at a given pH

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Results vary based on individual factors including diet, exercise, and metabolic baseline

PMID: 21030672 | doi:10.1152/japplphysiol.00945.2010 Zivanovic-Posilovic G et al

Because clearance is slow, an intolerable dose cannot be reversed quickly discontinuation does not produce prompt washout

Neither the thymosin fragment nor the body protection compound contains cysteine or methionine residues