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The medication primarily targets three areas
**Gallbladder Disease**: Some studies have found an increased risk of gallbladder problems, including gallstones, in patients taking GLP-1 agonists and dual agonists
7 Endocrine Therapy Interaction: The MD Anderson Cancer Center retrospective observational cohort study also found tamoxifen or aromatase inhibitor (AI) use is typically associated with weight gain of +2.3 kg ( P = .037)
Do note that GLP-1 medicines are not currently licensed for reproductive health, including the treatment of PCOS
Prioritize protein to preserve muscle mass during weight loss
The body compensates, and weight loss stalls
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