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Structured lifestyle modification programmes, as recommended by NICE guidance CG189, form the cornerstone of weight management for all patients, including those with Hashimoto's disease

Originally developed for glycemic control, these drugs are increasingly recognized for their capacity to induce autophagy, which may contribute to their cardioprotective effects

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This is why we discourage our patients from trying to self-medicate with over-the-counter GSH supplements

However, the effectiveness of oral supplementation has been a topic of debate, as some studies suggest that glutathione may be broken down in the digestive tract, limiting its absorption