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Key Takeaways GHK-Cu is a copper binding tripeptide, not a hormone It modulates extracellular matrix remodeling Its effects are local rather than endocrine Human evidence supports skin and wound applications Systemic anti aging claims exceed available data Sources Pickart L, Thaler MM

145 A double-blind trial comparing magnesium, 250 mg per day (formulation not reported), magnesium plus vitamin B6, and placebo demonstrated that magnesium plus vitamin B6 was the most and placebo the least effective in relieving PMS symptoms

Reconstituted aliquots are generally stored at 2-8C for short-term use

Robbins, Recent advances in the discovery of senolytics, Mechanisms of Ageing and Development, Volume 200, 2021, 111587

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