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In human erythrocytes, glutathione reductase (GR) catalyzes the reduction of glutathione disulfide to glutathione which maintains the reducing environment of the cell with the primary function of maintaining a high intracellular ratio of [GSH]/GR], where GSH is reduced glutathione
Le glutathion est un tripeptide donc il est form de trois acides amins : lacide L-glutamique, la L-glycine et la L-cystine
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In azoles, resistance is commonly attributed to overexpression of efflux pumps (particularly in Candida ) and alterations in the sterol biosynthesis pathway (Lee et al., 2021)
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