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6 Athira Pharma LIFT-AD topline results (press release)September 3, 2024 announcement that fosgonimeton (a distinct HGF/c-Met modulator) did not meet the primary or key secondary endpoints in the Phase 2/3 LIFT-AD Alzheimers trial

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The safety was preliminarily verified: The acute toxicity test showed that a single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice

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Preclinical colitis models: KPV reduces mucosal inflammation in preclinical colitis models, with demonstrated reductions in TNF-, IL-6, and other pro-inflammatory markers

Mutation at Cys2991 abolishes redox sensitivity while maintaining activation by DNA damage