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See supplemental appendix for more exclusions

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This dual mechanism of action often results in more significant weight loss compared to traditional GLP1 weight loss shots, making it an attractive option for weight loss doctors treating patients who need substantial weight reduction or who havent responded adequately to other medications

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While the powder is stable at room temperature for a period, the reconstituted liquid should be returned to the refrigerator as soon as you have finished your dose

The primary endpoints for this study were change in body weight and body composition (assessed by dual x-ray absorptiometry [DXA] scanning for total mass, fat mass, and lean mass), and we also assessed food intake, glycated hemoglobin (HbA1c%), and lipid profiles