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Testicular levels of IL-1 (Elabsciences, Cat N: E-EL-H0149, USA), IL-6 (Elabsciences, Cat N: E-EL-R0015, USA), and TNF- (Elabsciences, Cat N: E-EL-M3063, USA) were quantified using specific commercial ELISA kits according to the manufacturers instructions

Newer compounds like retatrutide add a third receptor target (GIP, GLP-1, and glucagon) and may create unique nutritional challenges that have not yet been well-studied

Purity verified at 99% by HPLC

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Addressing cost-related challenges and expanding research into new indications are crucial steps toward realizing the full potential of GLP-1 receptor agonists