Results Between January 1, 2016, and July 17, 2025, a total of 1,515 adult patients with T2DM who were prescribed a GLP-1 receptor agonist were screened
By binding to brain receptors that regulate hunger and appetite, GLP-1 alters food preferences and reduces calorie consumption
Semaglutide, the active ingredient of both oral and injectable Wegovy, copies GLP-1
The lyophilisation process removes water, eliminating the solvent that would otherwise allow hydrolysis reactions to degrade the peptide backbone
Here is the framework we use to match a patient to an approach
Thats because we did not have any pharmaceutical treatments (until ezdiffra (resmetirom) from Madrigal in 2024), and until late stage fibrosis & cirrhosis develops, most liver disease is fully reversible