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Furthermore, AdoCbl is intricately intertwined with energy metabolism and plays a pivotal role in the Krebs cycle, where one of the consequential products is acetyl-Co [74]

[54] This notion of using iron as a way to combat pathogens has led to a whole investigation of how iron deficiency could be used in the treatment of certain diseases

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This highlights why iron is critical for performance, and why an iron deficiency could potentially have detrimental impacts

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The body downregulates its basal metabolic rate to conserve energy, matching the lower caloric intake induced by the medication