Not recommended for children under 18, pregnant or breastfeeding women, or people with increased nervous excitability, insomnia, or hypertension
Using medication for weight loss can be a beneficial strategy for individuals who have struggled to lose weight through diet and exercise alone, especially those dealing with obesity-related health issues
They reduce sensations of hunger, and also seem to reduce impulsive human behaviour like binge-eating calorie dense foods
The relevance to humans is unclear, but these medications are contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
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Research protocols typically use dosing ranges of 200-500 mcg with flexible dosing schedules to optimize for research goals