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PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024
For some patients, especially those with low energy tied to nutritional gaps, support can make it easier to stay consistent
Rarely, some patients may experience a mild headache or light bruising
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But reduced appetite means reduced food intake, and reduced food intake can mean reduced nutrient absorption
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