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Theranostics 9, 19231951
25 Sci Rep
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As expected, the strictly conserved Asn419 hTrxR1 appears to be the most important residue for aligning the flexible C-terminal arm during catalysis, because a simultaneous mutation of all three guiding bar residues (Trp407 hTrxR1 , Asn418 hTrxR1 , and Asn419 hTrxR1 ) led only to a minor increase in hTrx1- and DTNB-reduction activity of hTrxR1 compared to the mutation of Asn419 hTrxR1 alone (Table 2)
J Ethnopharmacol 179:291330 Chen L, Zhu Y, Hu Z, Wu S, Jin C (2021) Beetroot as a functional food with huge health benefits: antioxidant, antitumor, physical function, and chronic metabolomics activity
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