You should not take cyanocobalamin-based products if you: Have a known cobalt allergy Have Lebers hereditary optic neuropathy , as B12 can worsen vision in this condition Discuss nasal B12 with your clinician first if you have: Severe megaloblastic anemia Polycythemia vera or other bone marrow disorders Low iron or folate Kidney disease Are undergoing chemotherapy or using bone marrow-suppressing drugs Are pregnant or breastfeeding Possible Side Effects Most side effects reported with B12 nasal products are mild and temporary: Slight nasal irritation, burning, or dryness Runny or stuffy nose, sneezing, or sore throat Mild headache Nausea or a brief metallic taste Tingling or pins and needles sensations, especially early on as nerves recover Serious reactions are rare but require immediate medical care: Rash, hives, or intense itching Swelling of the face, lips, tongue, or throat Trouble breathing or swallowing Fever, chills, or signs of infection that dont match a simple cold If anything feels out of proportion or youre unsure, stop the product and speak with your healthcare provider or seek urgent care

"Most people can be easily treated with injections or tablets to replace the missing vitamins," notes the NHS
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Its often used as a supplementary fat-burning aid
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Hempill-Bryant explains that babies born to B12 deficient mothers will also be deficient in B12, especially if they are then exclusively breastfed. A study in the Journal of Child Neurology found that the most severe cases of B12 deficiency can lead to weakness, failure to thrive, afebrile seizure, developmental delay, nystagmus, tremors, and involuntary movement among young babies