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Importantly, as the chief brain source of APOE, astrocytes, especially those expressing the APOE4 allele, promote A aggregation, tau pathologies, BBB breakdown, and cerebrovascular dysfunctions (Wang M

A meta-analysis including 3802 patients further consolidated these findings, reporting pooled complete clearance rates of approximately 91% for dysplasia and 78% for intestinal metaplasia after RFA

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