Melanoma Risk The relationship between MT-2 and melanoma is not definitively established, but the theoretical concern is significant: MT-2 stimulates melanocyte proliferation the same cell type that becomes malignant in melanoma At least 4 case reports link MT-2 use to melanoma diagnosis (Hjuler et al., 2014) No long-term safety data exists MT-2 has never completed Phase III trials for tanning However, it's important to note: Case reports cannot establish causation MT-2 users are often the same population that uses tanning beds (an established melanoma risk factor) The FDA-approved MT-1 (afamelanotide), which works through the same MC1R pathway, has not shown melanoma signals in clinical trials Bottom line: The risk is theoretical but plausible
For SureBeads, the beads were pre-incubated with the GFP antibody, washed, and then incubated with lysates for 1 h at 4 C with gentle agitation
doi:10.1002/cbdv.200690111
Sathananthan AH, Selvaraj K, Girijashankar ML, et al
Proc Am Assoc Cancer Res 46:5179, 2005
So, when taken together, women can find that the two complement each others effects
