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Injecting semaglutide in the morning could be advantageous for those who experience gastrointestinal side effects

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Besides obesity criteria, adults with a BMI between 27 and 29.9 can qualify if they have at least one weight-related comorbidity such as prediabetes, type 2 diabetes, or cardiovascular disease (Novo Nordisk Pharmaceuticals Ltd)

This dual-action gives Tirzepatide a unique advantage over Semaglutide, as it enhances its metabolic and weight loss effects

In contrast, sustained or recurrent heat stress may induce Sertoli cell dysfunction and dedifferentiation, disrupt the bloodtestis barrier, and ultimately lead to persistent spermatogenic impairment or, in severe cases, irreversible infertility (Hu et al., 2021