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Transthyretin amyloid cardiomyopathy: impact of transthyretin amyloid deposition in myocardium on cardiac morphology and function

Maeda K, Tomita Y

Tan JS, Wang JJ, Flood V, Rochtchina E, Smith W, Mitchell P

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This creates a powerful, dual-action synergistic effect: the L-Carnitine component ensures a steady supply of acetyl-CoA by transporting fats into the mitochondria, while the fumarate component accelerates the Krebs cycle's ability to process that fuel into usable cellular energy