Together with technological advances in quantitative mass spectrometry-based proteomics methods and improved affinity reagents, it has led to the development of new tools and workflows to study signalling by specific types of ubiquitin modifications [2,3,4]
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Research has found that exposing renal tubular epithelial cells to various concentrations of CaOx crystal solution results in a significant increase in the expression of ferroptosis-related proteins such as p53, ACSL4, transferrin receptor (TRC), and TF as the concentration of CaOx crystals increases
Zhu F, Yan P, Zhang J, Cui Y, Zheng M, Cheng Y, Guo Y, Yang X, Guo X, Zhu H (2019) Deficiency of TPPP2, a factor linked to oligoasthenozoospermia, causes subfertility in male mice
doi: 10.1530/EC-23-0462 16 GuoR.SpyropoulosF.MichelT
Such inhibition might diminish the inflammatory response, reducing cellular stress