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(15) El transportador activo de carnitina (OCTN) el cual es dependiente de sodio, se encuentra incluido en la familia de transportadores catinicos (OCT) y a su vez en la subfamilia OCTN (16), siendo ampliamente expresado en tejidos humanos como corazn (miocardio, vlvulas y arteriolas), msculo esqueltico, rion (tbulos proximales y distales, glomrulos), placenta, intestino delgado, y algunas reas cerebrales (corteza, hipocampo, cerebelo) (17,18), ocasionando su dficit

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doi: 10.1038/nrclinonc.2016.206 97 QuoyerJLonguetCBrocaCLinckNCostesSVarinEet al