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Constipation accompanied by severe abdominal cramping or bloating suggests severely slowed gut motility requiring dose reduction

These molecular changes were corroborated by enhanced cell viability in the GO@GSH-FA-treated SH-SY5Y cells subjected to OGD/R, as evidenced by flow cytometry assays (Figure 7)

Ethics declarations Funding The authors wish to thank Daniel Soares Freire, MD, PhD for providing medical writing and Cristiane Mapurunga Aoqui Guenoub, MD, PhD for providing assistance with English-language editing, both on behalf of Springer Healthcare

This delayed stomach-clearing action reduces appetite and promotes weight loss, but it can also trigger nausea, bloating, and acid reflux during the first 2-4 weeks of treatment

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Diet Strategy: Use Protein, Fiber, and Healthy Fats to Stay Fuller Longer Design plates to favor high-quality protein, fiber-rich vegetables, and whole grains, and moderate amounts of healthy fats from: Avocados Nuts Seeds Olive oil Protein increases satiety, and one trial found high-protein diets produced about 50 percent greater feelings of fullness than standard diets