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This may be explained by the findings of Albares and colleagues, Guinot and colleagues, and Kang and colleagues , who reported that pregnancy, use of hormonal contraception and lack of use of sunscreen are aggravating factors of melasma due to increase number and activity of melanocyte in epidermis

doi:10.1111/jcpt.13233 [7] Jia X, Zhai T, Qu C, et al

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Niektre leki podaje si raz dziennie, inne raz w tygodniu