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In the Phase 3b SURMOUNT-5 trial, participants who reached the maximum dose of tirzepatide achieved an average weight loss of 20.2% over 72 weeks
2023 DOI: 10.1056/NEJMoa2301972 PMID: 37366315 Read on PubMed Nature Medicine Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial Sanyal AJ, Kaplan LM, Frias JP, et al
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Small adjustments can go a long way
It is meaningful to further evaluate the relationship between long-term use of GLP-1RAs and the risk of respiratory diseases in the future