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Oxidative stress occurs when oxidants (reactive oxygen species) outweigh available antioxidants

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by silencing glycogen synthase kinase 3 beta (GSK-3) and the Wnt-pathway-inhibitor Dickkopf-1 (DKK-1) [23]

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For custom combination protocols where GHK-Cu is dosed alongside other compounds in separate vials, the GHK-Cu dosing is calculated independently and administered on its own schedule