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However, if taking it on an empty stomach causes mild gastrointestinal upset, taking it with a small, light carbohydrate snack can mitigate this issue without severely compromising absorption
Most patients find the experience straightforward and tolerable
One injection instead of two
Small boosts in VO 2 max/timetoexhaustion at 13 g doses
Metformin is now increasingly being used in combination with new incretin-based therapies: glucagon-like peptide 1 (GLP-1) analogues and dipeptidyl peptidase-4 (DPP-4) inhibitors [46], both of which enhance pancreatic beta cell function
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