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People with a heterozygous MTHFR have one normal gene and one altered gene
Irregular use creates gaps between doses, allowing oxidative stress to build up again before your next capsule
The conversion chart helps map equivalent doses, but the pharmacokinetic overlap means you may temporarily have elevated combined drug levels during the first two to three weeks of a switch
As such, low B12 levels can cause low oxygen levels and nerve problems
Think of injections as intensive treatment phases and topical application as maintenance between cycles
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