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One source says 250mcg

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IM up to 3/week provides less frequent, moderate dosing

It also aids in breaking down fats and proteins

An increase in the Akkermansia spp population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice (in Eng)

After initiation and dose increases, patients should be observed carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by vomiting)