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Epigenetic silencing of antigen presentation machinery, including Polycomb-mediated repression and DNA hypermethylation at the HLA class I/NLRC5/interferon axis, further diminishes peptide display and limits T cell recognition (36)
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Endocr Rev (2017) 38:189219
Vitamin B12 helps reduce the gastrointestinal side effects commonly associated with initiating GLP-1/GIP therapy, including nausea
Additionally, B12 helps lower homocysteine levels, which may reduce the risk of heart disease, heart attacks, and strokes
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