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B12 injections can help prevent or treat certain types of anemia caused by B12 deficiency, resulting in improved oxygen transport and increased red blood cell production
however, clinical trials have not consistently supported these uses
Ten of the 12 patients reported complete resolution of symptoms, with the remaining two experiencing an 80% reduction in symptoms
Cytokine signaling across the BBB: Even without direct entry, cytokines produced in response to LPS can signal through the circumventricular organs (areas of the brain where the BBB is naturally more permeable) or bind to endothelial receptors, triggering secondary messengers and inflammatory cascades in the CNS
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