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Hibernating mammals and newborn humans use uncoupler proteins to maintain body heat

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This pattern is reported across forums and is consistent with IGF-1's known effects on intracellular hydration and protein synthesis through PI3K/Akt/mTOR (Yoshida & Delafontaine, 2020)

the 'no DAC' form (Modified GRF(1-29)) does not, so it is short-acting