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Injecting too fast can create a bolus of medication that triggers a stronger local reaction
And human reports described onset around an hour with duration up to 20 hours an effect decoupled from drug presence
Compromised glutathione synthesis results in high susceptibility to acetaminophen hepatotoxicity in acatalasemic mice
Allen RH, Stabler SP, Lindenbaum J
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this is more of a supportive measure than an interaction concern
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