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The trial is registered with the University Hospital Medical Information Network (UMIN) Clinical Trials Registry (UMIN000011118)
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Apart from these substitutions, the sequence largely mirrors native GLP-1, so semaglutide retains potent agonism at the GLP-1 receptor while circulating far longer in the bloodstream, which allows for once-weekly subcutaneous or once-daily oral dosing options [4]
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Liver Disease During Pregnancy
