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The iron overload-induced oocyte damage and embryo toxicity might be related to ferroptosis mediated by multiple signaling pathways, including nuclear receptor coactivator 4-dependent ferritinophagy (123), glutathione peroxidase 4-dependent downregulation (124), and heme oxygenase 1 (HMOX1) overexpression (120), in which mitochondrial dysfunction and structural damage play a central role

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Bacterial and parasitic enteric infections are discussed in Chapters 42 and 43

Reta is of particular interest as a tool for comparing triple-pathway activity against single- and dual-agonist reference compounds

Childhood obesity is associated not only with poorer health, but also with lower educational attainment and, in turn, reduced economic opportunity later in life

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