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It is likely that the most well-known function of NADPH oxidase-derived superoxide is the inactivation of NO in the reaction that forms peroxynitrite, which leads to impaired endothelium dependent vasodilation and the uncoupling of endothelial NO synthase (eNOS) to produce additional superoxide

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Battifora M, Pesce G, Paolieri F, Fiorino N, Giordano C, Riccio AM, et al

It detoxifies your body's cells and it also recycles itself to increase the effectiveness of other antioxidants (Vitamins C, D, etc)

B12 shots are far superior to oral forms of B12 due to the fact that they have superior absorption and quickly get into your target tissues (where B12 has its action)

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models