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All the mutations (four nucleotide substitutions) detected are also found in the CYP21A (CYP21A1) pseudogene
Its levels also decline with age
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Working with gastroenterologists can help manage malabsorption
However, the evidence is modest , especially for cosmetic uses like skin-whitening, and the side-effects , while usually mild, must be taken seriously especially in certain populations (asthma, pregnant, on chemotherapy, etc.)
Comprehensive transcriptome and proteome analyses have provided global views of mRNA and protein abundance of metabolic enzymes in kidney regions and nephron segments 24,25,26,27 , which are generally consistent with results of previous targeted analyses of enzyme activity, protein abundance, or substrate utilization
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