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It is a living, ongoing relationship betwee

Another phase II study assessed the safety and efficacy of varying doses of retatrutide, included participants with a BMI of 25 to 50 kg/m 2 and an HbA1c of 7.0% to 10.5% [114]

meaning that animal studies have shown some adverse effect or there are no well-controlled studies in humans, but potential benefits may warrant use despite potential risks