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Then, glucagon-like peptide-1 agonists, more well known as GLP-1s, entered the picture, changing the conversation almost overnight

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review of literature Given the pathophysiological heterogeneity of HFpEF, our understanding has been constrained by limited access to human samples and the absence of animal models that fully replicate the human HFpEF phenotype

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The FDAs October 2023 Category 2 designation banned 17 peptides from all pharmacy compounding, citing theoretical risks rather than documented harm