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doi: 10.1158/2326-6066.CIR-17-0273
A small sample size combined with imprecise measurement can easily produce a "no change" finding when change actually occurred
Replace electrolytes through sports drinks, coconut water, or electrolyte mixes, not just water alone
As such, discontinuing therapy solely based on normalized HbA1c may deprive patients, especially those with underlying cardiovascular or renal risk, of organ-protective effects that are both substantial and sustained
BMI is a crude measure of adiposity that does not assess body composition or quantity of visceral fat, which has more deleterious effects in HFpEF 6,16 , limiting insight on the effect of semaglutide on visceral fat loss and its association with improvements in KCCQ-CSS and 6MWD outcomes
The above-mentioned Veterans Affairs study, for example, was skewed towards older white males
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