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A phase 2 trial published in the New England Journal of Medicine showed average weight loss of over 24% at 48 weeks, and the first phase 3 results in December 2025 suggested that average weight loss could be around 28 to 29%

In the biomarker discovery and validation set, the disease group consisted of a mixture of patients exposed and unexposed to drug treatment including antidepressants for the treatment of MDD

This approach makes it easier to identify the source of any adverse effects and allows your body to adjust incrementally

Longevity matters

So let's actually look at what BPC-157 is, what it does, and whether the hype matches the reality

However, in many cases, patients who want to take a GLP-1 for weight loss will find that they must pay for their treatment out-of-pocket