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Inhibition of the Xc- transport system and depletion of cystine The Xc- transport system, which is composed of SLC7A11 and SLC3A2 proteins imports cystine into the cell while exporting glutamate
GH peak around 40 minutes post-dose, half-life roughly 1.5-2.5 hours
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The pernicious anemias result from impaired DNA synthesis due to a block in purine and thymidine biosynthesis
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