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Trial data showed significant drops in non-HDL cholesterol, triglycerides, and high-sensitivity C-reactive protein (a marker of cardiovascular inflammation)
Duration The longest observation period was 9 weeks for semaglutide
In the reduced state, the thiol group of cysteine is able to donate a reducing equivalent (H++ e-) to other unstable molecules, such as reactive oxygen species
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In the STEP1 trial, weekly semaglutide 2.4 mg caused an average ~15% body weight reduction over 68 weeks, vs ~2.5% with placebonews.cornell.edunews.cornell.edu
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