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Quality of unregulated supply is also a real, separate risk
They range from mild to debilitating and life-threatening
doi: 10.1038/s41387-020-00142-z
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Retinol works through the retinoid receptor pathway (RAR/RXR), directly upregulating specific procollagen genes and inhibiting matrix metalloproteinases (MMPs) that break down existing collagen [6]
Often, this does not involve an allergic reaction, which is an immune response to a certain trigger that is too aggressive
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