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Until more evidence is available, in this individualized risk and benefit decision-making, one should not assume that this risk is specific to semaglutide. Taken in total, the summary noted that currently available evidence suggests a possible association between semaglutide and NAION

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Alexander-EL says

Lower blood sugar reduces the bodys demand for insulin, and with less circulating insulin, the ovaries produce less testosterone

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Discuss with your healthcare provider whether transitioning to a different GLP-1 receptor agonist is appropriate, as cross-reactivity is not guaranteed and many users who react to one medication tolerate another without difficulty