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Immune System Support
Pernicious anemia often leaves individuals feeling exhausted and weak, as a lack of B12 prevents the body from producing enough red blood cells, which are responsible for carrying oxygen to tissues and organs
Block NNMT, save the B3, raise NAD+, and fat cells start working more like lean tissue
Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study
In a 9-month monkey oral toxicity study, all female monkeys in the high-dose group showed minimal-to-slight periportal hepatocyte vacuolation
Vision loss.
