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Black cumin is part of the buttercup family and is primarily found in Turkey, Greece, India, and the Middle East

Both the CIR and the SCCS consider it safe at the concentrations used in cosmetics

Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B12 deficiency: randmised placebo controlled trial

10.1016/j.bmcl.2011.09.047 150 WortmannM.SchneiderM.PircherJ.HellfritschJ.AichlerM.VegiN.et al (2013)

Results with p 0.05 were considered statistically significant

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