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Wang DZ, Wang C, Wu H, Li ZM, Ye Q (2016) Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase

This work was supported by the Jining Key Laboratory of Pharmacology, Research Fund for Shandong Provincial Natural Science Foundation (No

& Slattery, J

Biol Psychiatry 73(2):e4e5

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In response to oxidative stress, this regulatory mechanism allows NRF2 to rapidly translocate to the nucleus and activate transcription of antioxidant and phase II detoxifying enzymes to effectively mitigate external insults (Figure 2)