The 0.25 mg starting dose is backed by data from the STEP and SUSTAIN clinical trial programs
Aside from prompting increased insulin production to lower blood sugar in diabetes treatment, higher GLP-1 levels interact with brain areas that regulate appetite and satiety
However, new research suggests a link between weight loss drugs and blindness (and other eye issues), leading some to refer to the issue as Ozempic blindness. A small study published in JAMA Ophthalmology analyzed data from nine patients who developed severe vision issues, including sudden blindness, while taking semaglutide (Wegovy, Ozempic) or tirzepatide (Mounjaro, Zepbound)
Dates, names, promises made, and outcomes delivered
Acta pharmacologica Sinica
If you notice a raised area of skin immediately after your injection, it could be a wheal (welt)